Preparation Process
Prepared using a gradient dissolution method:
Oxytetracycline base and magnesium oxide are mixed in a 35:2.4 ratio.
Sodium formaldehyde sulfoxylate is added as an antioxidant.
Dissolved in a glycerol formaldehyde and N,N-dimethylacetamide composite solvent (2.5:3.5 ratio).
The dissolution reaction is completed at a constant temperature of 55℃ under nitrogen purging.
After adjusting the pH to 8.6, the solution is sterilized through a 0.22μm microporous membrane.
Safety Specifications
Incompatibility: Do not use concurrently with penicillins or cephalosporins.
Residue Control: Discontinue use 28 days before slaughter in beef cattle/pigs.
Stability: Shelf life is 36 months; accelerated testing shows that the effective ingredient retention rate is >95% after 6 months of storage at 40℃.
Special Warning: Freezing of the solution will cause drug denaturation and inactivation.
